毕彩丰

毕彩丰，男;山东平度市人;汉族;中共党员;博士;现任中国海洋大学化学化工学院教授， 博士生导师。完成省级鉴定项目4项，都达到了国际先进水平。主持完成省、市科研项目7项;完成应用开发项目12项，累计创造经济效益过亿元。完成的医药中间体、原料药、精细化工新产品在国内外市场颇具竞争力。 已合成、表征了200多个新的化合物，发表论文60多篇，其中SCI收录6篇。目前在研项目5项，其中青岛市科技计划项目1项;海大兰太科技项目2项;海洋配位化学1项、新型Schiff碱配合物的合成与应用研究1项。

1982年 本科毕业于山东大学化学系;

2001年7月博士毕业于中国原子能科学研究院。

1988年任中国海洋大学化学化工学院讲师;1993年任副教授;1996年任教授。

主要研究方向:功能配合物化学、精细化学品化学。

配位化学、 热分析导论、有机合成前沿及本科生课程:无机化学、配位化学。

医药及中间体合成;新型功能配合物的合成;海洋资源利用技术与工程;精细化学品合成

1.新型氨基酸希夫碱铜配合物的合成及在抗肿瘤作用靶点-蛋白酶体中的应用，20971115，2010.1-2012.12，国家自然科学基金

2. 以小分子海洋生物活性物质为前躯物配合物的设计合成与抗肿瘤活性研究，21071134，2011.1-2013.12，国家自然科学基金

3. 油田采油综合节水技研究与示范的子课题: 星型聚酰胺-胺型破乳剂体系的研制。(2006BABO4BO2) 国家十一五科技支撑计划

4. 海洋赤潮毒素的毛细管电泳电化学在线快速检测新技术和新仪器(2007AA09Z113)，2007.10-2010.10，国家 863计划

5. 头孢类药物及中间体合成。

近1. Qiang Wang, Caifeng Bi, Yuhua Fan, Xia Zhang，Jian Zuo and Sanbin Liu. A novel copper(Ⅱ) complex with Schiff base derived from o-vanillin and L-methionine: Synthesis and crystal structure. Russian Journal of Coordination Chemistry, 2011, 37(3): 228-234. SCI2. Yuhua Fan, Yufang Wang, Caifeng Bi, QiangWang, Xia Zhang. Synthesis, crystal structure, and fluorescence properties of a two-dimensional copper(Ⅱ) complex with Schiff base. Russian Journal of Coordination Chemistry, 2010, 22(3):1689-1694. SCI5. Yan Xiao, Di Chen, Xia Zhang，Qiuzhi Cui, Yuhua Fan, Caifeng Bi, Qingping Dou. Molecular study on copper-mediated tumor proteasome inhibition and cell death. International Journal of Oncology，2010, 37(1):81-87. SCI 6. Xia Zhang, Michael Frezza, Vesna Milacic, LucaRonconi, Yuhua Fan, Caifeng Bi and Qingping Dou. Inhibition of tumor proteasome activity by gold- dithiocarbamato complexes via both redox-dependent and-independent processes. Journal of Cellular Biochemistry, 2010, 109:162-172. SCI 7. Yan Xiao, Caifeng Bi, Yuhua Fan, Shanbin Liu, Xia Zhang, Dongmei Zhang, Yilong Wang . Synthesis,characterization and bioactivity of Schiff base copper(Ⅱ) complexes derived from L-glutamine and L-asparagine. Journal of Coordination Chemistry, 2009, 62(18):3029-3039. SCI8. Qiang Wang, Caifeng Bi, Daqi Wang, Yuhua Fan. Dichlorido{N-[1- pyridyl] ethlidene]ethane-1,2-diamine}copper(Ⅱ). Acta Cryst. 2009, E65, m439 . SCI9. Qiang Wang, Caifeng Bi, Yuhua Fan. Tetra-μ-acetato-κ8O:O/-bis{[2-(2- furyl)- 1-(2-furylmethyl)-1H-benzimidazole-κN3]copper(Ⅱ)}. Acta Cryst. 2009. E65, m867-868. SCI10. Siquan Liu, Caifeng Bi, L.-Y.Chen and Yuhua Fan. 2-[(1,3-Benzothiazol-2-yl) iminomethyl] phenol, Acta Cryst. 2009. E65, o738. SCI11. Xinyu Liu, Yuhua Fan, Caifeng Bi, Yuan Gao. 2-Methoxy-6-[(Z)- [(5-methyl-2-pyridyl) iminomethyl]phenol. Acta Cryst. 2009, E65, o2170. SCI 12. Yan Xiao, Caifeng Bi , Yuhua Fan, Cindy Cui, Xia Zhang and Qingping Dou. L-glutamine Schiff base copper complex as a proteasome inhibitor and an apoptosis inducer in human cancer cells. International Journal of Oncology, 2008, 33: 1073-1079. SCI13. Xia Zhang, Caifeng Bi , Yuhua Fan, Cindy Cui, Di Chen, Yan Xiao and Qingping Dou. Induction of tumor cell apoptosis by taurine Schiff base copper complex is associated the with inhibition of proteasomal activity. International Journal of Molecular Medicine, 2008, 22: 677-682. SCI 14. Yuhua Fan , Feng Guo, Caifeng Bi, Dongmei Zhang , Yu Zhao, Jiakun Xu. Synthesis, characterization, and electrochemical studies on the interaction of binuclear Cu(Ⅱ) complex with DNA. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 2008, 38(7): 573-576. SCI 15. Yuhua Fan, Zixian Gao, Caifeng Bi, Sitan Xie, Xia Zhang. Synthesis and thermal decomposition kinetics of La(Ⅲ) complex with unsymmetrical Schiff base ligand. Journal of Thermal Analysis and Calorimetry, 2008, 91(3):919-923. SCI16. Yuhua Fan , Yingying Li, Caifeng Bi, et al. Synthesis, characterization, and prohibitive action on free radical O2-· of β-phenylalanine Schiff base binuclear complexes. Russian Journal of Coordination Chemistry, 2008, 34(10):772-774. SCI17. Yuhua Fan, Qiang Wang, Caifeng Bi. Poly[tris(μ3-5-aminoisophthalato) diaquadicerium (Ⅲ)]. Acta Cryst. (2008). E64, m1326. SCI18. Yan Xiao, Caifeng Bi, Yuhua Fan, et al. 1,1/,5,5/-Tetramethyl-2,2/-diphenyl-4,4/- [p-phenyl-enebis(methylidymenitrilo)]di-1H-pyrazol-3(2H)-one. Acta Cryst. 2008， E64, o1479. SCI19. Caifeng Bi, Xia Zhang, Yuhua Fan, et al. Synthesis and thermal decomposition kinetics of uranium(Ⅵ) complex with unsymmetrical Schiff base ligand. Chinese Journal of Chemistry, 2008, 26(2): 265-268. SCI 20. Aidong Wang , Caifeng Bi , Yuhua Fan, et al. Structure and coordination environment of the zinc complex with vanillin of double-stranded helix. Russian Journal of Coordination Chemistry, 2008, 34(7): 475-479. SCI21. Yuhua Fan, Xuetao He, Caifeng Bi, Feng Guo, Yan Bao and Rong Chen. Synthesis, characterization and antibacterial activity of new rare-earth complexes with unsymmetrical Schiff base ligand. Russian Journal of Coordination Chemistry, 2007, 33(7):546-549. SCI22. Yuhua Fan, Yanna Zou, Caifeng Bi, Aidong Wang and Feng Guo. Synthesis, crystal structure and thermal decomposition kinetics of Zn(Ⅱ) complex with vanillin. Russian Journal of Coordination Chemistry, 2007, 33(8):582-587. SCI23. Caifeng Bi, Aidong Wang, Yuhua Fan, Yanna Zou, Xia Zhang. Synthesis, crystal structure and theoretical calculation of Ni (Ⅱ) complex with N,Nu2032-1,2-cyclohexenylenebi s(salicy- lideneimine). Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 2007, 37(1) :67-71. SCI24. Caifeng Bi, Xiaokang Ai, Yuhua Fan, Shuangyu Bi, Sitan Xie. Synthesis and thermal decomposition kinetics of La(Ⅲ) complex with unsymmetrical Schiff base. Journal of the Chilean Chemical Society, 2007, 52(4): 1126-1128. SCI25.Lirong Yang, Caifeng Bi, Yuhua Fan. Crystal structure and thermodecomposition kinetics of copper(Ⅱ) ternary complex with o-vanillin-taurine Schiff -base and 1,10-phenanthroline. Asian Journal of Chemistry, 2007, 19(1) : 195-204. SCI26.Feng Guo, Caifeng Bi, Yuhua Fan, Yan Xiao, Xuetao He and Jiakun Xu. Synthesis, crystal structure and antibacterial properties of N-(2-Hydroxy-1- naphthalidene)-4-aminoantipyrine. Asian Journal of Chemistry, 2007, 19(3): 1846-1852. SCI27. Fan Yuhua, Bi Caifeng, Ai Xiaokang, Yaosen Xue, Xuetao He, Yan Xiao. Synthesis and thermal decomposition kinetics of Er(Ⅲ) complex with unsymmetrical Schiff base ligand. Journal of Coordination Chemistry. 2006, 59(14/20): 1575-1581. SCI28. Yuhua Fan, Caifeng Bi, Siquan Liu. Synthesis and thermal decomposition kinetics of Th (Ⅳ) complex with unsymmetrical Schiff base ligand. Journal of Radioanalytical and Nuclear Chemistry, 2006, 267(1): 89-93. SCI29. Yuhua Fan, Caifeng Bi. Synthesis, characterization and thermodecomposition kinetics of Sm(Ⅲ) complex with unsymmetrical Schiff base zwitterion ligand. Chinese Journal of Chemistry, 2006, 24(3): 371-374. SCI30. Yanna Zou, Yuhua Fan, Caifeng Bi. Synthesis and crystal structure of Zn (Ⅱ) complex with 2-aminopyridine and acetylacetone. Journal of Structural Chemistry, 2006, 25(3): 261-264. SCI31. Xiaokang Ai, Caifeng Bi, Yuhua Fan. 2-[(2-Aminophenylimino) (phenyl)-methyl]-4-chlorophenol.Acta Crystallographica Section E. 2006,E62, o3475-o3476. SCI32. Lirong Yang, Caifeng Bi, Yuhua Fan. Crystal structure and thermodecomposition kinetics of a three-dimensional supramolecular Mn comlplex with 8-hydroxyquinoline. Russian Journal of Coordination Chemistry, 2006, 32(7):504. SCI33. Caifeng Bi, Xiaokang Ai, Yuhua Fan. Synthesis, characterization and thermal decomposition kinetics of unsymmetrical Schiff base complex with samarium (Ⅲ). Journal of Rare Earths, 2006, 24(Suppl.):7-10. SCI期发表代表性文章

1989年获山东省科技进步二等奖;

1990年获山东省发明成果二等奖;

1991年获国家星火二等奖;

1990年获教育部科技进步二等奖;

1997年获山东省教育厅科技进步三等奖。

1992年被评为国家建材局优秀青年科技工作者;

1994年获山东省优秀青年知识分子称号;

1995年被评为全国优秀教师;

1995年享受国务院特殊津贴;

1997年被评为山东省专业技术拔尖人才;

2001年济南市客座专业技术拔尖人才。